Biology 385 CELL BIOLOGY
Fall 2014
Class Times: Lecture: Monday,
Wednesday, 12:00 - 12:50 in FSC 016
Lab: Tuesday
FSC 132, 8:30-10:30; 11:00-1:00
Text: Cell and Molecular Biology: Concepts and Experiments,
7th Edition by Gerald Karp ISBN 978-1118206737
Instructor: Dr. Bill Patrie |
Campus Phone: (717) 477-1400 |
Office: FSC 152 |
Email: wjpatr@ship.edu |
Web Page: http://webspace.ship.edu/wjpatr/ |
Office Hours: Monday 1-3, Tuesday 1-2, Wednesday 1-2:30, Friday 11-1, by appointment, and by chance. If not in my office I’m usually in 132 (cell lab), 137 (across from the cell lab), or room 2. |
General Class Information
|
The Textbook The author includes review questions at the
end of each chapter section that focus primarily on the key "facts"
presented in that section. These are useful to test how well you
understand and assimilate important concepts. Try to answer these
questions as you read the chapters. Having those questions in front of
you can also be helpful when reading the chapters, allowing you to
concentrate on the key concepts. Analytic questions at the end of
each chapter tend to be experimental or application oriented. Some are
pretty straight-forward, others can be challenging. Make a good effort
to answer them before resorting to the answer key. The acts of
contemplation and problem solving are crucial to applying concepts and true
learning; looking up answers to a question without thinking only answers that
one question. In the sciences, we are always facing new questions
and challenges. |
Labs |
GENERAL CLASS POLICIES Attendance: There is a
high correlation between class attendance and class performance (i.e.,
grade). I occasionally take attendance and give extra credit points to
those present. Do not miss labs. Make arrangements in
advance if you do need to miss a lab. Each unexcused absence from a
lab will result in a 25 point deduction from your grade. Classroom etiquette:
Please turn off cell phones, ipads, etc. during
lecture. Please refrain from talking in class. Ringing cell
phones, texting, and talking during class are unnecessary
distractions. If you use a laptop for taking notes, check with me
beforehand and sit near the front (it's easy to get distracted with the
internet and games just a click away). Likewise, let me know if
personal situations necessitate keeping a cell phone on. If you want to
record lectures, just let me know. During exams, electronic devices
other than a calculator should be off and put away in a bag or
backpack. Lab
periods are less formal and you will obviously need to talk to your lab
partners. |
Grades A= 90 and above; B=80-89; C=70-79; D=60-69;
F= less than 60. |
Class and Lab
Schedule- Warning! Subject to mutations and
rearrangements! Last Updated 8/24/2014
DATE |
TOPIC |
CHAPTER |
Mon 8/25 |
Overview of cell structure and function |
1 |
Tues 8/26 |
Lab/Lecture - biological molecules, Protein
Structure and Function |
2 |
Wed 8/27 |
Protein Structure and Function |
2 |
Mon 9/1 |
Labor Day - no class |
|
Tues 9/2 |
Lab # 1 Protein Structure
Computer Tutorial Web Link Handout |
|
Wed 9/3 |
DNA, replication, genes, and gene
expression – an overview |
|
Mon 9/8 |
Bioenergetics-general |
3 |
Tues 9/9 |
Lab # 2 Protein assay in class Amino acid quiz |
18* |
Wed 9/10 |
Protein Methods/Cell Methods |
18* |
Mon 9/15 |
Membranes and transport |
4 |
Tues 9/16 |
Lab # 3 Cell Methods, Cell
culture basics |
|
Wed 9/17 |
Membranes and transport |
4 |
Mon 9/22 |
Cytoskeleton |
9 |
Tues 9/23 |
Lab # 4 Immunofluorescence (Formal report) |
|
Wed 9/24 |
Cytoskeleton |
9 |
Mon 9/29 |
Cellular membrane systems |
8 |
Tues 9/30 |
Lab # 4 continued |
|
Wed 10/1 |
Exam 1 Chapters 1-4, 18*, 9 |
|
Mon 10/6 |
Cellular membrane systems |
8 |
Tues 10/7 |
Lab # 5 Cell Fractionation/Western Blot Immunofluorescence
report due |
|
Wed 10/8 |
Cellular membrane systems –
Mitochondria, chloroplasts, peroxisomes |
5.1,5.6, 6.1, 8.9 |
Mon 10/13 |
Fall Break - no class |
|
Tues 10/14 |
Fall Break - no lab |
|
Wed 10/15 |
Cellular membrane systems -
nucleus |
12.2 |
Mon 10/20 |
Extracellular matrix and
cellular interactions |
7 |
Tues 10/21 |
Lab # 5 Continued |
|
Wed 10/22 |
Metabolism |
3,5 |
Mon 10/27 |
Metabolism |
3,5 |
Tues 10/28 |
Lab # 5 continued |
|
Wed 10/29 |
DNA, replication, genes, and gene
expression – some details |
10,11, 12, 13 |
Mon 11/3 |
DNA, replication, genes, and gene
expression – some details |
10,11, 12, 13 |
Tues 11/4 |
Lab # 6 Protein
and DNA Sequence Analysis Web Link Handout |
|
Wed 11/5 |
Exam 2 Chapters 8, 3,5, 6.1, 7, 12.2 |
|
Mon 11/10 |
Cell Signaling |
15 |
Tues 11/11 |
Lab # 7 Detection of EGFR gene by PCR
(Formal report) |
|
Wed 11/12 |
Cell Signaling |
15 |
Mon 11/17 |
Cell Signaling |
15 |
Tues 11/18 |
Lab # 7 continued; Lecture: DNA Techniques |
18* |
Wed 11/19 |
Cell Cycle Control |
14 |
Mon 11/24 |
Cell Cycle Control |
14 |
Tues 11/25 |
TBA |
|
Wed 11/26 Wed-Sun |
Happy Thanksgiving! |
|
Mon 12/1 |
Cancer |
16 |
Tues 12/2 |
Lab Final |
16 |
Wed 12/3 |
Cancer
lab notebooks due |
16 |
Exam week |
Final Test Chapters 10-13 (parts) 15, 14,
16 ,18* |
*Chapter 18 covers many
varied techniques; appropriate sections will be incorporated into specific
topics as needed